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Empower women with Overactive Bladder (OAB) to improve their bladder health so that they can live healthier and happier lives.
To investigate the feasibility acceptability and preliminary efficacy of a digital intervention, the OAB App, for the conservative management of overactive bladder.
Design
• Single arm, pre-test post-test trial
• Clinical Trial registration number: NCT05170100
Inclusion criteria
• On waiting list
• Referred for OAB from GP
• Symptoms of OAB to include at least one of the following: urgency of urination, frequency of urination or urge of incontinence.
• Female
• Own a smartphone
Exclusion criteria
• Active/Recurrent urinary tract infection
• Urinary retention
• Bladder Pain Syndrome/Interstitial cystitis
• Pelvic/gynae cancer
• Pregnant
• Dementia
• Kidney problems
• Stroke
• Have/had a neuro-stimulation implant for treatment of OAB
Recruitment
• Clinics contacted patients with brief study description and a recommendation to participate
• Patients completed online ‘consent to be contacted’ form
• Study team provided participant information leaflet
• Participants completed online informed consent form and downloaded the OAB app
Outcomes
• 72 hour digital bladder diary
• Incontinence Questionnaire Overactive Bladder (ICIQ-OAB)
• Incontinence Questionnaire Overactive Bladder: Quality of Life (ICIQ-OABQoL)
The OAB app improved patients’ quality of life by reducing the symptoms of urgency, frequency, nocturia and incontinence.
Patients using the OAB app experienced:
• significant reduction in OAB symptoms
• significant improvement in quality of life
• significant decrease in frequency of urination
• reduction in average number of incontinence episodes
The OAB app provides potential for the conservative management of patients with OAB.
Sooknarine C, Salameh F, Burke N, Staunton B, Carr E, Sexton K, Agnew G, Downey A, D’Arcy F, Sarma S, Cundiff G
100% of participants (n=18) reported a reduction in theirOAB symptoms
Paired samples t tests
Significant difference in ICIQ-OAB scoresa:
• Between baseline (M = 7.13, SD = 2.53) and week 4 (M = 5.19, SD = 2.46; t(15) = 3.78, p =.002).
• Between baseline and week 8 (M = 5.00, SD = 2.52; t(16) = 5.28, p < .001).
83% of participants (n=18) reported an improvement in their Quality of Life
Paired samples t tests
Significant difference in ICIQ-OAB-QoL scoresa:
• Between baseline (M = 84.45, SD =20.50) and week 4 (M = 69.06, SD = 22.14; t(15) = 3.12, p = .007).
• Between baseline and week 8 (M = 62.41, SD = 31.28; t(16) = 3.52, p = .003).
Bladder Diary Results: Frequency reduced to within normal range
Significant difference in Frequency of Urination between baseline (M = 10.19, SD 3.41) and week 8 (M = 6.71, SD = 1.25; t(6) = 3.28, p = .017).
Bladder Diary Results: Incontinence episodes
Incontinence Episodes at Baseline: M = 10.00, SD = 15.17Incontinence Episodes at Week 8: M = 3.57, SD = 4.58
Take a smartphone photo of this QR code to view the complete protocol or visit:
www.clinicaltrials.gov/ct2/show/NCT05170100
The following centers took part in our pilot study:
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